Printable Poly(N-acryloyl glycinamide) Nanocomposite Hydrogel Formulations

Abstract Printable synthetic polymer formulations leading to hydrogels with high strengths, swelling resistance, and bioactivities are required control the mechanical functional characteristics of biological scaffolds. Here, we present nanocomposite prepared upper critical solution (UCST)-type ink poly( N -acryloyl glycinamide) (PNAGA) different concentrations carbon nanotubes (CNTs). Nanofiller CNTs recommended for increasing hydrogel Printing methods were established in which included before after fabrication ink. The compared each other their temperatures shear-thinning properties determined from rheologies. A self-thickening method was utilized 3D printing constructs, printabilities varied CNT content preparation method. After photopolymerization printed exhibited a slightly higher strength (15,500 Pa, E mod = 0.697 ± 0.222 MPa), great elasticity (elongation ~500%) an electrical conductivity (5.2‧10 −4 1.5‧10 S‧m −1 ) comparable that neat PNAGA hydrogel. Since high-strength constructs can be good resolution low cytotoxicity, these scaffolds could used tissue engineering applications.